Lexaurin 3mg/30tbl

Composition of

1 tablet contains the active ingredient: bromazepamum (bromazepam) 1.5 mg Other ingredients: lactose (lactose), maize starch (corn starch), povidone (povidone), magnesium stearate (magnesium stearate), talc (soapstone)

1 tablet contains the active ingredient: bromazepamum (bromazepam) 3 mg Other ingredients: lactose (lactose), erythrosinum (erythrosine E 127), maize starch (corn starch), povidone (povidone), magnesium stearate (magnesium stearate), talc (soapstone)

Pharmacotherapeutic group

Benzodiazepine anxiolytic

Characteristic

Bromazepam is a benzodiazepine anxiolytic. Low-dose bromazepamu reduce psychological stress and fear without affecting physical activity. High doses produce sedation and muscle-relaxing effect, which is important in the treatment of severe neurotic and psychosomatic disorders.

Indications

Anxiety, tension, irritability, sleep disturbances. Functional disorders of the cardiovascular system, respiratory, gastrointestinal and genitourinary system caused by stress, anxiety and tension. Other psychosomatic disorders such as headaches or skin disorders of psychological origin. Anxiety and stress in chronic organic diseases. Withdrawal symptoms (symptoms after stopping alcohol with dependents).

Contraindications

Acute glaucoma, myasthenia gravis, hypersensitivity to benzodiazepines, severe respiratory insufficiency, acute intoxication by alcohol or drugs which have a depressant effect on central nervous system (barbiturates, neuroleptics, antidepressants, other anxiolytics, antihistamines)

Side effects

The high dose was well tolerated Lexaurinu. In sensitive patients may experience mild fatigue, drowsiness, dizziness, vertigo and rarely muscle weakness. The above side effects can be avoided by adjusting the dose. Very rarely you may experience headaches, confusion, impaired coordination, and behavioral disorders

concentration, speech, memory loss, incoherent articulation, decreased libido, hypersensitivity reactions. As with other benzodiazepines may be prolonged treatment with high doses of drug addiction develop. Exceptionally, paradoxical reactions may occur as with other benzodiazepines. If there is agitation, increased muscle tension, sleep disturbances or hallucinations, bromazepamom treatment should be discontinued.

Interactions

Concomitant use of alcoholic beverages enhances the effect bromazepamu. Bromazepamu sedative effect may enhance the drugs affecting the central nervous system (neuroleptics, antidepressants, other anxiolytics, hypnotics, analgesics, anesthetics, antihistamines), so caution should be exercised in such combinations.

Dosage

Dosage is individual. Outpatient treatment is started with low doses, which may increase if necessary to achieve optimal effect. The average dose for outpatients is 1.5 to 3 mg two or three times a day. Hospital patients are treated with 6 to 12 mg two to three times a day. The maximum daily dose is 60 mg divided into 2-3 doses. Long-term treatment should not be abruptly discontinued, dosage should be gradually reduced. In elderly patients it is recommended to reduce the recommended dose in half.

Attention

Pregnancy and lactation

Lexaurin is not recommended during pregnancy except in emergencies where the benefit to the mother would override the risk to the fetus. Bromazepam passes into breast milk, therefore breastfeeding should be discontinued during treatment.

Overdose

Taking more tablets may cause disturbances of consciousness, which can result in coma, reduced to the disappearance of reflexes, respiratory insufficiency, and even respiratory arrest especially with the current alcohol intoxication or other drugs with depressant effects on central nervous systém.Účinným specific antidote is flumazenil. Its effect is much shorter duration than bromazepam, therefore requires close supervision for several hours after waking the patient, if necessary dose of flumazenil must be repeated.

Lexaurin should be used cautiously and gradually the old and the dumb and patients with organic changes in the CNS. People prone to abuse of psychoactive substances such as alcoholics and people addicted to drugs, which are treated bromazepamom must be strictly observed. Patients with severe renal and hepatic insufficiency should be closely monitored. Bromazepam is not recommended as monotherapy in depressive and psychotic patients. The safety and benefits of taking bromazepamu in children is not yet sufficiently investigated.

The effect on psychomotor performance

Llexaurin psychomotor reactions can affect the patient, especially when taken together with alcohol or drugs with CNS depressants. Your doctor or pharmacist must notify the patient especially when drives a motor vehicle or operating machines during treatment.

Warning

Do not use product after expiration date indicated on the label.

Packaging

30 tablets containing 1.5 mg of 30 tablets containing 3 mg

Retention

Store below 25 ° C, protected wet. Keep out of reach of children.